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The neuroprotective effect of GLP-1R agonists is that it can either directly/locally cause neuroprotection by acting on neuronal tissue or indirectly/systemically cause neuroprotection by improving glycemic control and treating existing insulin resistance (Figure 3) ( FIGURE 3 Alzheimers Disease Several early studies have identified the presence of cognitive impairment in patients with T2D (Perlmuter et al., 1984

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Tirzepatide reduces hunger signals, but eating large meals forces your slowed stomach to work harder, triggering nausea and potential vomiting

Potential Pitfalls and How to Avoid Them Let's talk about the other side of the coin