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H 2 S can directly donate electrons to the mitochondrial electron transport chain (ETC) at complex II and increase mitochondrial cAMP, whereas at higher concentrations, it disrupts the ETC by inhibiting mitochondrial cytochrome c oxidase (Szabo et al ., 2014)

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showed that GPX4, ACSl4, iron and malondialdehyde (MDA) in myocardial ischemic tissue did not change significantly after 15, 30 or 60 min of coronary artery occlusion [88]