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A meta-analysis of six randomized trials that compared 3 to 6 months of postoperative treatment with a gonadotropin-releasing hormone agonist (GnRH), danazol, or combined oral contraceptives with no postoperative treatment of placebo revealed a significant reduction in pain scores at the conclusion of therapy in the active-treatment groups, although the benefits were inconsistent with longer follow-up (to 18 months) after discontinuation of therapy (22)