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Outcome Measures The measured outcomes included changes in hepatic steatosis severity, liver enzyme levels (aspartate transaminase [AST] and alanine transaminase [ALT]), serum lipid profile (triglycerides [TG], total cholesterol [TC], low-density lipoprotein cholesterol [LDL-C], and high-density lipoprotein cholesterol [HDL-C]), glycemic markers (fasting blood glucose [FBG], fasting insulin levels, and insulin resistance assessed via the homeostatic model assessment for insulin resistance [HOMA-IR]), oxidative stress markers (glutathione, malondialdehyde [MDA], and total antioxidant capacity [TAC]), and the inflammatory marker C-reactive protein [CRP]

Formation of hydrogen peroxide Hydrogen peroxide (H2O2) is one of the ROS formed by mitochondria during aerobic respiration

And both come from the same pharmaceutical company, Eli Lilly

Written informed consent was obtained from the parents of all enrolled patients