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ALA is often referred to as a universal antioxidant because it can act as an antioxidant in both lipophilic and hydrophilic settings to reduce byproducts of oxidative metabolism, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) (Figure 4) [29]

Studies have shown that the composition and function of the intestinal microbiota are altered in RA patients, with reductions in microbial species such as Faecalibacterium, Flavobacterium, Bifidobacterium, Bacteroides, and Haemophilus and increases in Lactobacillus, Prevotella, and Clostridium [76, 77]

Stay Properly Hydrated Proper hydration is essential for the body's detoxification processes

Modifiers of Redox Regulation as A Therapeutic Target for Als Only two drugs are currently approved by the USA Food and Drug Administration (US FDA-FDA) for ALS treatment