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Results Evidence suggests that GLP-1RAs mitigate psoriasis severity through systemic effects, including weight loss and improved glycemic control, and local immunomodulation, such as the regulation of invariant natural killer T (iNKT) cells and AMPK activation in psoriatic plaques

Nabrdalik, K

And thats because we're waiting on more long-term data that shows there is a sustained clinical benefit with these medications. To note: Wellmark covers GLP-1s when used as a treatment for type 2 diabetes

Severe complications it lists include acute pancreatitis confirmed by elevated lipase and amylase, plus acute kidney injury arising from dehydration