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Observational studies have produced inconsistent findings, and there is a notable absence of large-scale randomized controlled trials to validate the efficacy of lowering uric acid levels

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Ethics declarations Funding This work was supported by the National Natural Science Foundation of China (82103475), Hebei Province Natural Science Foundation (H2023307028, H2024206056), the Medical Science Research Project of Hebei Provincial Health Commission (20240370), Hebei Province Medical Adaptation Technology Tracking Project (GZ2024002), and Hebei Province Government-Funded Clinical Medicine Excellent Talent Training Program (ZF2025013)

Sin embargo, algunos riesgos potenciales incluyen: Malestar en el lugar de la inyeccin: Moretones, hinchazn o enrojecimiento en el lugar de la inyeccin intravenosa o intramuscular