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7 Limitations and future prospects The clinical translation of morin and similar phytochemicals faces significant challenges, including poor bioavailability, limited human pharmacokinetic data, and natural product variability

isolated cagrilintide had a smaller effect

In addition, the suppression of EPO on hepcidin expression may be related to the erythroferrone (ERFE) produced by erythroblasts in response to EPO, which could target hepatic BMP/SMAD signaling via preferentially impairing an evolutionarily closely related BMP subgroup of BMP5, BMP6, and BMP7 [5456]