side effects semaglutide vs tirzepatide Comparative safety and of and tirzepatide: Implications for clinical decision-making in obesity management which has less side effects

Simultaneous GLP-1 and insulin administration acutely enhances their vasodilatory, antiinflammatory, and antioxidant action in type 2 diabetes

Both Zepbound and Wegovy can help with weight loss, but they work slightly differently in your body

Common, usually mild: Injection-site reactions (redness, swelling, itching), most frequent with both Mild headache, dizziness, or flushing after injection Initial water retention as IGF-1 rises Transient fatigue in the first 12 weeks Less common, dose-dependent: Carpal tunnel-like wrist symptoms (sign IGF-1 may be too high) Joint discomfort or stiffness Numbness or tingling in extremities Elevated blood glucose (GH antagonizes insulin) The monitoring that matters:IGF-1 (insulin-like growth factor 1, the downstream marker of GH activity) is the lab value that tells you whether youre in a therapeutic range or pushing past it

If a person stops taking Wegovy, they may regain some of the weight they previously lost