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The most reliable indicator of potency loss is reduced effectiveness, specifically, diminished appetite suppression at a dose that previously worked

This treatment mimics the GLP-1 hormone, targeting brain regions that control appetite and food intake, effectively reducing hunger and enhancing feelings of fullness

Medicare: Now covers Wegovy for patients with a BMI $\ge$ 27 AND a history of heart disease

Some data suggests stability extends to 28 days at controlled room temperature for specific brand-name formulations, but remember, those formulations contain stabilizers that compounded versions typically lack