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) Specifically, the changes to the gut microbiome composition caused a reduction in the intestinal cells that produce mucin, which is the barrier that prevents microbes from causing inflammation in the gut

Acid reflux and gas Other GI side effects may include gas (burping, flatulence), indigestion, and acid reflux, though these are less common than side effects like nausea and vomiting

Users considering combining phentermine with semaglutide should be aware that phentermine can also affect GI function, though typically in the opposite direction (stimulant effects may partially offset semaglutide slowing)

Slow Gastric Emptying: Rybelsus slows the rate at which food passes through the gastrointestinal tract, which promotes a longer feeling of fullness and reduces the frequency of meals