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Obesity and insulin resistance, which commonly characterized this syndrome, prompted the design of studies investigating the effects of glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1RA) in PCOS

These observations emphasized the cooperative nature of CRL4 DET1-COP1 and showed enhanced substrate ubiquitination when COP1 is incorporated into CRL4 DET1 assemblies

Data on the study organism, the type of resistance, the analysis methods, and, where applicable, the gene loci of interest were extracted from the studies