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The findings highlight the importance of considering symptoms and comorbidities when managing pts with PBC, as recommended by treatment guidelines

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however, these remain investigational and their clinical significance requires further study For detailed pharmacology and mechanism of action, refer to the MHRA Electronic Medicines Compendium (EMC) Summaries of Product Characteristics (SmPCs) for individual GLP-1 receptor agonists (e.g., semaglutide [Ozempic/Wegovy], liraglutide [Victoza/Saxenda], dulaglutide [Trulicity]) and the corresponding EMA EPARs

GLP-1R immunofluorescence in DRG neurons