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13(1) : 812 Saibal K Biswas, Irfan Rahman Environmental toxicity, redox signaling and lung inflammation: the role of glutathione Mol Aspects Med Feb-Apr 2009

upregulates VEGF, BDNF, and BMP-2 expression

Inhibition of the system xc GSHGPX4 axis can predispose cells to ferroptosis, while the primary initiation of ferroptosis typically occurs through the accumulation of toxic lipids, as discussed later in the section

However, engineered bacterial therapy faces severe biosafety, ethical, and regulatory challenges, including the stability of engineered bacteria in vivo , risks of horizontal gene transfer, immunogenicity, and controllable clearance from the body