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Here are some common side effects of tretinoin: Skin irritation Peeling and flaking Increased sensitivity to sun Dryness Skin redness Tingling or burning sensation May cause hyperpigmentation in skin of color due to irritation 20 Increased breakouts in the beginning of the treatment (commonly referred to as tretinoin purging) It is recommended that women stop using tretinoin one month before planning a pregnancy, during pregnancy, and until they are nursing

Estimated absolute differences in outcomes with SGLT-2 inhibitors and GLP-1 receptor agonists compared with placebo per 1,000 people with type 2 diabetes with moderate and very high cardiovascular risk, treated for five years

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