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Hypoglycemia, cardiovascular outcomes, and death

Dose titration (gradually increasing from 0.25 mg to 1.0 mg weekly) is clinically proven to maximize results while minimizing nausea and GI upset

In another study conducted in mice with Alzheimer disease in the final stage, intraperitoneal liraglutide improved spatial memory, reduced amyloid deposition and inflammation, and increased dentate gyrus neurogenesis, suggesting that, besides exerting preventive effects, this GLP-1RA may reverse some of the key pathological findings of Alzheimer disease

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