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The top hits include Trp-catabolism the OVX animals plasma showed high level of KYN and that was reduced by EB-treatment, the KYN/Trp ratio was significantly high in the OVX animal compared to the OVX+E2 treated group

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Its not clear that this would be as effective in people who werent so obese, Felson said, noting that people with lower BMIs may not see as extreme results.

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Warner TD, Mitchell JA (2004) Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

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