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She went from weighing 244 pounds in February 2022 to 222 pounds by May, taking weekly injections of Wegovy
American Society of Nuclear Cardiology
In the alpha cells of the islets, GLP-1 receptor activation suppresses glucagon secretion, a process mediated by somatostatin release from adjacent delta cells.54,57 Beyond the pancreas, GLP-1 receptors are widely expressed in extrapancreatic tissues, including the heart, vascular smooth muscle, lungs, liver, gastrointestinal tract, vagus nerve, and enteric nervous system.58 GLP-1 receptor agonists exhibit varying degrees of homology with endogenous GLP-1 but possess extended durations of action
J Clin Invest (2008) 118(11):3693700.10.1172/JCI36461 28 WuTZhaoBRBoundMJChecklinHLBellonMLittleTJet alEffects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
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