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GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models Glucagon-like peptide-1 receptor (GLP-1R) agonists improve glycemic control and promote weight loss in diabetes and obesity but are also associated with gastrointestinal adverse events, including nausea and emesis in many patients

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Maaser C, Kannengiesser K, Specht C, Lgering A, Brzoska T, Luger TA, et al

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