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Certain antifungal medications such as ketoconazole and itraconazole, which require gastric acid for dissolution and absorption, may have reduced bioavailability when administered with semaglutide

Vitamin D Of all the nutrient gaps linked to GLP-1 use, vitamin D deficiency appears to be the most common, affecting 13.6% of users within a year

Thus, GLP-1 drugs present both an opportunity and a challenge for health systems and their leaders should actively consider how they will respond