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For example, researchers from a 2016 review of data on the gut-brain axis and BPC-157 explain that the peptide could maintain gastrointestinal mucosa, modulate serotonergic and dopaminergic systems, regenerate peripheral nerves, protect certain neurons, counteract various types of lesions, promote wound healing, and more.7 Some of these possible benefits are due to BPC-157s promotion of the cell migration of vascular endothelial cells.24 This means that the peptide can encourage the formation of new blood vessels (also known as angiogenesis)

But heres where berberine shows added benefits: its impact on gut microbiota and lipids makes it more than just a duplicate of metformin

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Proc Natl Acad Sci U S A (2008) 105(38):146927.10.1073/pnas.0802675105 171 DragosDGilcaMGamanLVladAIosifLStoianIet alPhytomedicine in joint disorders