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List of differentially abundant KOs across the treatment groups, compared to T1 (0mg/kg) Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

The lack of adequate human pregnancy data means healthcare providers cannot confidently guarantee fetal safety, making avoidance the standard recommendation

The 12 mg group achieved 24.2% weight loss at 48 weeks in Phase 2, and 28.7% at 68 weeks in the Phase 3 TRIUMPH-4 trial

They were then treated with the first dose of Semaglutide along with the above instructions