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These encouraging results mean that prospective trials are needed to determine whether GLP-1 receptor agonists can be repurposed as gerotherapeutics, say the authors

Across the entire trial (week 0 to 88) for the TRE, significantly more patients in the tirzepatide group achieved a body weight loss of 5% (97.3% vs 70.3% for the placebo

The category of CNS drugs illustrates this latter trend

If reconstituted incorrectly, researchers risk peptide aggregation, reduced bioactivity in assays, and irreproducible data across experimental replicates