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Even though it is not usually the first option people think of for weight loss today, it still has a place for some patients

Sustained UPR can promote the development of MAFLD by regulating lipogenesis, causing inflammation, and inducing hepatocyte death (Lebeaupin et al., 2018

It is evident from a growing number of studies that high-fat diets, drugs (antibiotics), and toxicants induce dysbiosis and improve the survivability of normally uncommon gut microbial species, leading to enhanced functional responses, pathogen infiltration, and further deterioration of gut health (Vascellari et al., 2021)

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