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De asemenea, n meta-analize, peste 70-80% dintre pacieni tolereaz bine tratamentul pe termen lung, cu efecte secundare gastro-intestinale (grea, diaree) care scad semnificativ dup perioada de iniiere (primele 4-8 sptmni)

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Patients should disclose a history of pancreatitis, gallbladder disease, severe gastrointestinal disease, kidney disease or other dehydration risks, use of diabetes medications such as insulin or sulfonylureas, pregnancy or plans for pregnancy, any personal or family history of medullary thyroid carcinoma or MEN2, and a history of diabetic retinopathy