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Other causes, like the formation of scar tissue (fibrosis), residual fat, and uneven skin texture as the body adjusts, are also possible

While semaglutide remains highly effective, recent studies compared it to tirzepatide (Mounjaro for diabetes, Zepbound for obesity), a dual GIP/GLP-1 receptor agonist targeting two hormone receptors

Peer review Peer review information Nature Aging thanks Christian Hlscher, Tami Rubinek and Marc Schneeberger for their contribution to the peer review of this work

Scientists are still unsure why this is, but there are two leading theories: Creatine helps muscles relax faster, which enables you to generate high amounts of force quickly and repeatedly