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What we know Replacing saturated fat with a mixture of omega-6 and omega-3 PUFA is associated with a significant reduction in total cholesterol, but clinical trials have failed to find a reduction in the risk of cardiovascular events

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Here's what the data show: 60% of lost weight returns within 1 year Regain starts within weeks not months Your hormones fight you for YEARS after weight loss But the regain curve decelerates

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One common side effect of GLP-1 medications is a reduced thirst drive

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Degradation of extracellular GSH, in a similar approach to degradation of extracellular cystine or cysteine 9 , is an additional potential approach

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