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Expected results: 15-20% total body weight loss over 68 weeks (clinical trials) Real-world: 25-40 pounds for someone starting at 200 pounds Steady weekly loss averaging 1-2 pounds per week at therapeutic dose Dosing protocol: Week 1-4: 0.25mg once weekly Week 5-8: 0.5mg once weekly Week 9-12: 1mg once weekly Week 13-16: 1.7mg once weekly (optional) Week 17+: 2.4mg once weekly (maximum dose) Use our semaglutide dosage calculator for precise dosing and reconstitution
But as evidence propositions they are worlds apart: one is an FDA-approved drug with replicated Phase 3 trials, the other is an unapproved research chemical with two small surrogate-marker studies and discontinued development
Martnez, Y
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