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The predominant unknown covalent impurities account for up to 10% of the total peptide composition, accompanied by altered molecular structures with completely unknown pharmacological and toxicological properties

The author makes nine assumptions to justify increasing the final infusion of NAC, including that 25-50% of the APAP will become NAPQI and that no further absorption of acetaminophen will occur after the initial overdose

Phosphate-buffered saline (PBS) was administered intranasally to the healthy control group

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