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The mechanisms contributing to this combination's efficacy may include central potentiation of hypothalamic interleukin-6 (IL-6) activity enabling post-leptin receptor potentiation of leptin action, as genetic or pharmacological interruption of IL-6 action attenuates the weight loss activity of amylin in mice [16]

Learn more about the latest #obesity data from Kailera Therapeutics here: To view or add a comment, sign in Wegovy secures CDSO approval for MASH indication in India Novo Nordisk India has received regulatory approval from the Central Drugs Standard Control Organisation (CDSO) for a new indication for Wegovy (semaglutide injection 2.4 mg)

One puzzling finding in our study is the reduced risk of infectious diseases such as pneumonia and sepsis