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Vitamin B12 and One-Carbon Metabolism Vitamin B12 (cobalamin) is an essential cofactor for several enzymes involved in one-carbon metabolism and energy-related pathways: Methionine Synthase: B12-dependent remethylation of homocysteine to methionine is central to the generation of S-adenosylmethionine (SAM), a universal methyl donor used in DNA, protein, and phospholipid methylation

Swelling usually peaks in the first 24 to 48 hours, then eases over 5 to 10 days, with full settling over 2 to 4 weeks

Instead, opt for nutrient-dense, whole foods that keep you satiated and energized throughout the day