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Cataract exhibited the shortest mean onset time, averaging 125.5 days, suggesting that the lens may be particularly sensitive to the pharmacological effects of chloroquine and HCQ, with damage manifesting within a relatively short period

Collectively, these strategies demonstrate that metabolically targeting TAM subsets is a powerful approach to controlling ferroptosis, suggesting multiple avenues for combination therapies that integrate ferroptosis inducers, immune checkpoint modulators, and metabolic inhibitors

wrote the main manuscript text