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It has been clearly demonstrated that altered circulating thyroid hormone is associated with various mental signs and symptoms, such as emotional disturbances (impulsiveness, irritability), cognitive deficits (impairments in memory, concentration, attention, planning, and productivity), and affective symptoms (anxiety, depression, mania), which increase the incidence of neuropsychiatric disorder like depression (111)

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(2010) The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor