Neuro Endocrinol Lett 32:13340, PMID: 21552194 Kaddurah-Daouk R, Yuan P, Boyle SH, Matson W, Wang Z, Zeng ZB, Zhu H, Dougherty GG, Yao JK, Chen G, Guitart X, Carlson PJ, Neumeister A, Zarate C, Krishnan RR, Manji HK, Drevets W (2012) Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile
Integrating ChIP-seq, HiC, and PRO-seq datasets, we revealed broad functional binding of NRF2 at enhancer elements, including NRF2-dependent enhancer-derived RNA (eRNA) synthesis and extensive linkages between NRF2 target promoters and enhancers
Understanding the terminology: The MTHFR C677T variant is a single nucleotide polymorphism (SNP)
mtGSH preserves mitochondrial membrane potential (m) and limits oxidative membrane damage, thereby preventing CYCS release 39