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421 Collectively,these results demonstrated that epigenetic silencing of IRGs is a viral strategy to escape immune surveillance and promote viral propagation, which is overall beneficial to viral oncogenesis of human gamma-herpesviruses, considering that these IRGs possess antiviral activities against these oncoviruses

Whole blood was collected by a 0.5-mm Goldenrod Animal Lancet (MEDIpoint, New York, NY, USA) puncture of the submandibular vein at 100, 200, 300, 400, 500, 600, 700, and 800 days after irradiation

Statistical analyses were performed using the Prism software (9.2.0), unless otherwise specified in the figure legends

& Salvi, R