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Statistical analysis for ERG readings were done by comparing scotopic or photopic amplitudes between NAC, NACET and Vehicle, at each light intensity using MannWhitney non-parametric analysis

Many patients report a reduction in appetite and improved blood sugar control within this time frame, which can lead to gradual weight loss

Complementing these findings, preliminary data from human synovial fibroblasts show that GLP-1 stimulation reduces cytokine production and alters inflammatory gene expression, suggesting broader immunomodulatory effects across key synovial cell populations

Non-selective profile distinct from next generation analogues (afamelanotide MC1R selective, bremelanotide MC4R preferential)