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FIG 5 Roles of T4C and MT4C in the antioxidative-stress defense

they frequently lack appropriate specificity, chemical stability, or interference resistance to cellular components [115] and they are mostly incapable of simultaneously quantifying the intricate network of interconnected redox couples (e.g., GSH/GSSG, NAD/NADH, and Trx redox states) with adequate sensitivity under physiologically relevant conditions [116]

doi:10.3389/fphar.2014.00151 Mytilineou C1, Kramer BC, Yabut JA