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A major developmental study of compulsivity trait using magnetisation transfer (MT) imaging to quantify network connectivity in adolescents found that a composite compulsivity score (OCI plus Padua scale) was related to reduced growth of the MT trajectories in fronto-striatal circuity, most markedly in dorsolateral and dorsomedial prefrontal regions, including the SMA, consistent with our findings in this region, and further supporting a possible causal role of the changes in neural network function in OCD 2

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