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Oral tablets do not require the use of needles are typically taken daily can result in side effects such as nausea, vomiting, constipation, and abdominal pain must be taken on an empty stomach first thing in the morning, without eating for 30 minutes afterward Injections require the use of needles are typically taken once per week may cause side effects such as injection site reactions but may also cause nausea, vomiting, constipation, and abdominal pain can be taken regardless of whether you consume food or liquid beforehand or afterward You can inject semaglutide into your upper arm, thigh, or stomach

Factors like facial structure, neck circumference, and genetics also play important roles

The medication's effects on glucose regulation and appetite suppression diminish after discontinuation, as the drug has a half-life of approximately five days, meaning it clears from the system within several weeks

You are still appropriately hungry and will eat about 1/3-1/2 less food a day