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Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells
118,119 Furthermore, SIRT1 negatively regulates the NLRP3 inflammasome, suppressing pyroptosis and protecting hepatocytes from excessive immune-mediated damage
J Obes Metab Syndr 32(1):2545 Tian S, Zhou S, Wu W, lin Y, Wang T, Sun H, et al (2025) GLP-1 Receptor agonists alleviate diabetic kidney injury via -klotho-mediated ferroptosis inhibition
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