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Description

A molecular mechanism to diversify Ca 2+ signaling downstream of Gs protein-coupled receptors

The differential insulinotropic potency and other physiological effects of GIP and GLP-1 in both healthy individuals and those with T2DM may be linked to their distinct receptors and the downstream G proteins that transmit signals intracellularly

Concentration expresses how much active drug is dissolved in a given volume of solution, typically measured as mg/mL