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In immunosuppressed individuals, the symptoms are particularly severe and can be fatal

Gut Hormone Implicated in NMOSD-Related Brain Inflammation The gut hormone glucagon-like peptide 1 (GLP-1) and its receptor (GLP-1R) may contribute to brain inflammation and nerve overactivity in patients with neuromyelitis optica spectrum disorder (NMOSD)

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Neurons responsiveness to hunger and satiety signals (as ghrelin, cholecystokinin, and PYY) are also modulated by body energy stores (represented by leptin and insulin).3 The aim of this article is to review the role of gut hormones as mediators of feeding behavior and of the different nutrients in modulating gut hormones production