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The majority of serine catabolism involves its conversion to glycine, followed by glycine decarboxylase-mediated metabolism as detailed in the Amino Acid Catabolism page

Lemborexant: Concomitant administration of fluconazole increased lemborexant Cmax and AUC by approximately 1.6-and 4.2-fold, respectively which is expected to increase risk of adverse reactions, such as somnolence

Although small molecules, such as polyphenols, in food have been found to activate GPCRs 12,13,14 , the specific ligandreceptor combinations are poorly understood