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Frias JP, Deenadayalan S, Erichsen L, et al

The reasons are multifactorial, but one key obstacle is limited access

That difference can matter once treatment begins, especially when building habits, managing side effects, or maintaining results over time

The addition of GIP seems to: Improve insulin sensitivity Reduce compensatory metabolic slowdown Enhance fat loss , particularly subcutaneous fat Retatrutide Retatrutide is a triple agonist (GLP-1, GIP, and glucagon) currently under investigation