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Toxicol Environ Chem 90:739753 Geier DA, Kern JK, Geier MR (2017) Increased risk for an atypical autism diagnosis following thimerosal-containing vaccine exposure in the United States: a prospective longitudinal case-control study in the vaccine safety datalink

More important, H 2 O 2 diffuses into the cytosol where it continues to activate ASK1/2 and, thus, JNK, which causes ROS release from complex I, and the cycle begins again, augmented by ROS from complex III, especially if NAPQI is still being formed ( Figure 16 & 17 )