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Patients in Hathaway et al.s study were recruited from a neuro-ophthalmology clinic at a tertiary care institute who very likely have significant underlying symptoms and neuro-ophthalmic diseases that distinctly differ from those of the general population taking GLP-1RAs, potentially causing a selection bias, they wrote
Laboratory Studies If the patient is suspected of having primary carnitine deficiency or other metabolic disorders associated with secondary carnitine deficiency and is presenting with a metabolic emergency, the following studies are indicated [1, 2, 3, 14, 15] : Immediate assessment: Immediately check blood glucose and urine ketones if a child presents to the emergency room with lethargy, seizures, apnea, or any episode of decreased consciousness