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Menopausal status, hormone replacement therapy use and risk of self-reported physician-diagnosed osteoarthritis in women attending menopause clinics in Italy

(1) ROS directly attacks the mitochondria of chondrocytes, causing leakage of the electron transport chain (ETC) and further generating superoxide anion (O ), which forms a vicious cycle, inducing collapse of mitochondrial membrane potential and ATP synthesis disorder

Ginkgolide B inhibits PAF, which reduces leukocyte adhesion and subsequent inflammatory reactions, thereby sparing retinal endothelial cells [321]

The sample blank is not affected because the calibration curve is created based on the slope of the calibration curve