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Patients should seek emergency medical help (call 999) if they experience: Difficulty breathing, wheezing, or throat tightness Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticarial rash (hives) developing rapidly Dizziness, fainting, or rapid heartbeat suggesting anaphylaxis These symptoms typically occur within minutes to hours of administration, most commonly with injectable preparations

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doi: 10.1016/S03037207(01)003860 279 NohMYKimYSLeeKYLeeYJKimSHYuHJet al

Safety Precautions and Contraindications Both cryotherapy and BPC-157 carry safety considerations that require attention before initiating combined protocols