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doi: 10.3389/fnmol.2021.793004 Received 11 October 2021 Accepted 29 November 2021 Published 17 December 2021 Volume 14 - 2021 Edited by Inmaculada Segura, Ludwig Maximilian University of Munich, Germany Reviewed by Jong-Woo Sohn, Korea Advanced Institute of Science and Technology, South Korea

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IH has received nonfinancial support from AstraZeneca/Bristol Myers Squibb, Dexcom, GlaxoSmithKline, Insulet Corp., Janssen, Lexicon Pharmaceuticals, Medtronic, Merck & Co., Novo Nordisk, the Population Health Research Institute and Sanofi