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Depending on your genotype, this variant may have a modest to meaningful influence on hormonal signaling, libido regulation, and sexual function pathways

However, recent studies demonstrated that it is possible to re-sensitize tumors using a combination of molecules specifically reverting the aberrant DNA methylation in cancer cells (through drugs inhibiting DNA methyltransferase activity) and cytotoxic drugs (Plumb et al., 2000

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Carter JM, OHara C, Dundas G et al (2012) Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with neuroblastoma-like schwannomatosis and a novel germline SMARCB1 mutation